She also denied Halep yet another chance to move up to No. 1 in the Women's Tennis Association (WTA) rankings.
It's no secret I love Halep's game and think she can go as far as she wants as long as she avoids the occasional drops in confidence that impact her game so much. "I was looking to play my game, to be aggressive since the first moment".
Back in 2016, after winning her maiden Grand Slam at Roland Garros, Muguruza lost her path for nearly a year only to emerge earlier this year as the new Wimbledon champion.
"Whatever comes I will just take it", said Pliskova.
The 23-year-old once again proved how dominant she can be on a championship stage and will look to parlay her most recent title against world-class competition into even more success in her next marquee match.
"It was a very long time that I don't play with Halep, but she's playing very good". So it really shocked me.
Halep's coach, Darren Cahill, told ESPN the French Open loss still haunts her, saying: "There's still a little leftover residue from Paris".
Perhaps that had something to do with the poor showing. "I think I did few little mistakes and my shots were very, you know, placed, and I think I was doing nearly everything right there".
"We must not believe that because I won here, I'm going to win the US Open, the majors are completely different", she warned. But it's still there. "Maybe one day I will be there".
Halep reached the last eight in Cincinnati for the fifth straight year, contesting the final in 2015 and the semi-finals last year in the hard court run-up to the US Open.
Muguruza improved to 2-0 in 2017 finals and 5-3 career.
She gained a second-set edge with a backhand victor on break point for a 4-2 lead before closing it out in 1 hour, 19 minutes.
"I have the desire", Halep said after her match.
To have been within a whisker of the World No. 1 spot before walking out on court, only to be battered off the court, Halep remained poised and indeed at times brutally honest about what happened out there.
Biles joked she has done little more than walk her dog since she left Brazil, though that's hardly true.
Dimitrov, a champion at Brisbane and Sofia this year, jumped ahead 5-2 in the tie-break and took the first set when an Isner backhand went wide.
The Bulgarian won the tournament not dropping a set and losing his serve only once.
Kyrgios had only two break chances and failed to convert either during the one-hour, 25-minute final.
"Patience. That's what it is", Dimitrov said. "There's so many things going through your head". I feel like a lot of people are asking me about No. 1, stuff like that. "I'm pretty confident after that win". I knew that he's going to serve big, bold serves.
In the first Masters final featuring two players yet to win a 1000 series event since Guillermo Canas beat Andy Roddick in Toronto in 2002, Dimitrov always held sway.